Stand-in Romsey skipper Martin Weeks won the toss and decided to bat first. Opening batsmen Jack Salter and Tom George got the visitors off to a flying start and even after Salter was caught out, George continued firing, reaching his maiden half-century.
He was eventually out for 56 but Stuart Wood maintained Romsey’s good start with some powerful hitting of his own once he had played himself in.
A quick-fire 26 from Jamie Beard alongside a superb unbeaten knock of 79* guided the away side to 258-8 from their 42 overs.
With Twyford chasing a big total for victory, their opening partnership looked to get off to a quick start. They began well, hitting 80 before the partnership was broken by Cam Melling, removing Nick Moreland for 41.
Rhys Mitchell-Lee then picked up a couple of wickets as the Twyford innings began to fall apart.
Once Weeks came on to bowl, the hosts stood no chance of victory, with the captain for the day picking up the final six wickets of the match in devastating bowling spell which secured victory and full points for Romsey.
Twyford (174 all out) lost to OTs & Romsey IV (258-8) by 85 runs